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Genetic mapping

AP Biology Campbell 9th Chapter 20 outline

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Chapter 20 Biotechnology Lecture Outline Overview: The DNA Toolbox ? In 1995, researchers sequenced the entire genome of a free-living organism, the bacterium Haemophilus influenzae. ? A mere 12 years later, genome sequencing was under way for more than 2,000 species. ? By 2007, researchers had completely sequenced hundreds of prokaryotic genomes and dozens of eukaryotic ones, including all 3 billion base pairs of the human genome. ? Rapid advances in DNA technology?methods of working with and manipulating DNA?had their roots in the 1970s. ? A key accomplishment was the invention of techniques for making recombinant DNA, DNA molecules formed when segments of DNA from two different sources?often different species?are combined in vitro.

DNA Technology and Genomics

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Chapter 20 DNA Technology and Genomics Overview: Understanding and Manipulating Genomes One of the great achievements of modern science has been the sequencing of the human genome, which was largely completed by 2003. Progress began with the development of techniques for making recombinant DNA, in which genes from two different sources?and often different species?are combined in vitro into the same molecule. The methods for making recombinant DNA are central to genetic engineering, the direct manipulation of genes for practical purposes. Applications include the introduction of a desired gene into the DNA of a host that will produce the desired protein.
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