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Molecular genetics

Types of chromatin

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Chromatin: Types of chromatin Chromatin In non-dividing cells, the DNA exists as chromatin and appears uncoiled and randomly dispersed After DNA replication (S phase) the chromatin begins to condense in preparation for mitosis Chromatin consists of 50% DNA, 50% proteins, mainly histones Chromatin is the structure that the eukaryotic genome is packaged into It allows long molecules of DNA to fit into the small volume of the nucleus The basic structural unit of chromatin is the nucleosome Further folding and compaction of chromatin produces visible metaphase chromosomes during cell division Heterochromatin vs Euchromatin Euchromation Active Chromatin The majority of chromatin is this form Less condensed, lightly packed in the nucleus (basic ?beads on a string? form ?check)

Chp 12 Bio

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Overview: Locating Genes Along Chromosomes ? Mendel?s ?hereditary factors? were genes, though this wasn?t known at the time. ? The location of a particular gene can be seen by tagging isolated chromosomes with a fluorescent dye that highlights the gene. Concept 12.1 Mendelian inheritance has its physical basis in the behavior of chromosomes ? The chromosome theory of inheritance states: ? Mendelian genes have specific loci (positions) on chromosomes ? Chromosomes undergo segregation and independent assortment. ? The behavior of chromosomes during meiosis was said to account for Mendel?s laws of segregation and independent assortment. Morgan?s Experimental Evidence & Choice of Experimental Organism

Molecular Basis of Inheritance

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Chapter 16: The Molecular Basis of Inheritance Overview: Life?s Operating Instructions Watson and Crick introduced the double-helical model for the structure of DNA DNA is the substance of inheritance encoded in chemical language of DNA and reproduced in all the cells of your body it is DNA that directs the development of many different types of traits Concept 16.1: DNA is the genetic material The Search for the Genetic Material: Scientific Inquiry the role of DNA in heredity was first worked out by studying bacteria and the viruses that infect them Evidence That DNA Can Transform Bacteria Griffith worked with a pathogenic and nonpathogenic strain

AP Bio Campbell 7E Chapter 19 Test Bank

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Ch 19 Multiple Choice Identify the letter of the choice that best completes the statement or answers the question. ____ 1. The condensed chromosomes observed in mitosis include all of the following structures except a. nucleosomes. b. 30-nm fibers. c. 300-nm fibers. d. looped domain. e. ribosomes. ____ 2. Under the electron microscope, unfolded chromatin resembles "beads on a string." What do the "beads" represent? a. nucleosomes b. ribosomes c. beadosomes d. molecules of DNA polymerase e. molecules of RNA polymerase ____ 3. In a nucleosome, what is the DNA wrapped around? a. polymerase molecules b. ribosomes c. mRNA d. histones e. nucleolus protein

AP Bio Campbell 7E Chapter 17 Test Bank

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Ch 17 Multiple Choice Identify the letter of the choice that best completes the statement or answers the question. ____ 1. Garrod hypothesized that "inborn errors of metabolism" such as alkaptonuria occur because a. genes dictate the production of specific enzymes, and affected individuals have genetic defects that cause them to lack certain enzymes. b. enzymes are made of DNA, and affected individuals lack DNA polymerase. c. many metabolic enzymes use DNA as a cofactor, and affected individuals have mutations that prevent their enzymes from interacting efficiently with DNA. d. certain metabolic reactions are carried out by ribozymes, and affected individuals lack key splicing factors. e.

AP Bio Campbell 7E Chapter 16 Test Bank

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Ch 16 Multiple Choice Identify the letter of the choice that best completes the statement or answers the question. ____ 1. For a couple of decades, biologists knew the nucleus contained DNA and proteins. The prevailing opinion was that the genetic material was proteins, and not DNA. The reason for this belief was that proteins are more complex than DNA. This is because a. proteins have a greater variety of three-dimensional forms than does DNA. b. proteins have two different levels of structural organization; DNA has four. c. proteins are made of 20 amino acids and DNA is made of four nucleotides. d. Only A and C are correct. e. A, B, and C are correct. ____ 2. In his transformation experiments, Griffith observed that a.

Gene Regulation powerpoint

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Chapter 18: Regulation of Gene Expression Correlations to AP Bio Course Curriculum See Unit 3 Essential Knowledge document for all EK statements for Chapter 18. Correlations to AP Bio Course Curriculum Learning Objective 3.18: The student is able to describe the connection between the regulation of gene expression and observed differences between different kinds of organisms. Learning Objective 3.19: The student is able to describe the connection between the regulation of gene expression and observed differences between individuals in a population. Correlations to AP Bio Course Curriculum Learning Objective 3.20: The student is able to explain how the regulation of gene expression is essential for the processes and structures that support efficient cell function.

Ap Biology Chapter 15 Review

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Chapter 15 The Chromosomal Basis of Inheritance Overview: Locating Genes Along Chromosomes Mendel?s ?hereditary factors? were genes, though this wasn?t known at the time Today we can show that genes are located on chromosomes The location of a particular gene can be seen by tagging isolated chromosomes with a fluorescent dye that highlights the gene Concept 15.1: Mendelian inheritance has its physical basis in the behavior of chromosomes Mitosis and meiosis were first described in the late 1800s The chromosome theory of inheritance states: Mendelian genes have specific loci (positions) on chromosomes Chromosomes undergo segregation and independent assortment The behavior of chromosomes during meiosis was said to account for Mendel?s laws of segregation and independent assortment

15_Lecture_Presentation

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Chapter 15 The Chromosomal Basis of Inheritance Overview: Locating Genes Along Chromosomes Mendel?s ?hereditary factors? were genes, though this wasn?t known at the time Today we can show that genes are located on chromosomes The location of a particular gene can be seen by tagging isolated chromosomes with a fluorescent dye that highlights the gene Copyright ? 2008 Pearson Education Inc., publishing as Pearson Benjamin Cummings Fig. 15-1 Concept 15.1: Mendelian inheritance has its physical basis in the behavior of chromosomes Mitosis and meiosis were first described in the late 1800s The chromosome theory of inheritance states: Mendelian genes have specific loci (positions) on chromosomes Chromosomes undergo segregation and independent assortment

chapter 12 note

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Chapter 12 The Cell Cycle and Mitosis The Key Roles of Cell Division Cell division functions in reproduction, growth, and repair Unicellular organisms (ex. Amoeba) will divide to reproduce entire organisms Cell division also will allows a multicellular organism to develop from a single cell The Key Roles of Cell Division DNA is passed from one generation of cells to the next without dilution. -cell duplicates it DNA - moves the 2 copies to opposite ends of the cell - and then splits into 2 daughter cells The Key Roles of Cell Division Concept 12.1 Cell Division distributes identical sets of chromosomes to daughter cells A cell?s genetic material is called its genome - prokaryote = single long DNA strand - eukaryote = number of DNA molecules Concept 12.1

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