3088421638 | Carbohydrates Empirical Formula | (CH2O)n | | 0 |
3088424332 | Carbohydrate functions | 1)Energy Storage (NOT THE MAIN ONE)
2)Cell to Cell Signaling | | 1 |
3088428991 | Covalent bonds much more varied for carbs.
Therefore, what does this imply? | Vast array of 3-D structures and a variety of isomeric forms | | 2 |
3088430159 | Monosaccharides nomenclature | Aldehydes=Aldoses
Ketone=Ketoses
Example=D-Fructose is the most abundant ketohexose | | 3 |
3088435699 | Proteins use L isomers while sugars use... | D isomers | | 4 |
3088436157 | Epimers | Molecules that differ in configuration at only one chiral carbon | | 5 |
3088445825 | In solution the which form of sugar dominates? | Cyclic | | 6 |
3088450868 | Six-membered Ring | Pyranose | | 7 |
3088451534 | Five-membered Ring | Furanose | | 8 |
3088452280 | alpha vs. beta configurations | Alpha=down
Beta=up | | 9 |
3088453571 | Monosaccharides | aldehydes or ketones that have two or more hydroxyl groups. Smallest ones have atleast three carbons | | 10 |
3088455763 | Reducing Sugar | -Can reduce other molecules and therefore are oxidized.
-In open form have an aldehyde group
-Fructose is a non-reducing sugar | | 11 |
3088460734 | Advanced glycation end products(AGEs) | Binding of sugars to proteins that have been implicated in pathological conditions | | 12 |
3088464568 | Anomeric Carbon bound to Alcohol | Glycosidic or O-glycosidic bond | | 13 |
3088465781 | Anomeric Carbon bound to Amine | N-glycosidic bond | | 14 |
3088466331 | Oligosaccharides | link tow or more sugars through O-glycosidic bonds | | 15 |
3088467507 | Glycosyltransferases | -catalyze glycosidic bond formation on any of the hydroxyl groups on sugar
-Lots of hydroxyl groups =>diversity of bonds=>Different enzymes needed to make different bonds
-1to2% of the genome | | 16 |
3088473312 | UDP-Glucose | activated sugar nucleotide that has energy needed to form a glycosidic bond. |  | 17 |
3088475150 | Glucosinolates | -Special class of glycosides in plants
-Hydrolyzed into isothiocynate which is bitter
-Discourages herbivory | | 18 |
3088478146 | Sucrose | -alpha-Glucose to beta-Fructose |  | 19 |
3088479366 | Lactose | -Galactose to Glucose
-Beta 1to4 glycoside |  | 20 |
3088494760 | Maltose | -Glucose to Glucose
-Alpha 1 to 4 glycoside |  | 21 |
3088498876 | Glucose | -Reducing Sugar
-Down, Up, Down |  | 22 |
3088499794 | Fructose | -Non-reducing sugar
-Up, down |  | 23 |
3088501258 | Galactose | -Reducing Sugar
-Down, Up, Up |  | 24 |
3088504218 | Polysaccharides | Large polymeric oligosaccharides | | 25 |
3088504789 | Homopolymer | Polymer made up of same monomer | | 26 |
3088505703 | Glycogen | -Common in muscle and liver
-Main strand is alpha 1 to 4 glycosides
-Branching is alpha 1 to 6
-Forms hollow helix that allows more compact storage and easier access for enzymes |  | 27 |
3088510850 | Starch | -Nutritional reservoir in plants
-Amylose
-Amylopectin
-Hydrolyzed by alpha-amylase | | 28 |
3088512293 | Amylose | unbranched alpha-(1,4) glycosides |  | 29 |
3088520547 | Amylopectin | -Branched at every thirty units
-alpha (1to4) linkages
-alpha (1to6) linkages |  | 30 |
3088524048 | Cellulose | -Most abundant organic compound in Biosphere
-Long chains interact through H-bonding to generate rigid, supportive structure
-High tensil strength
-Beta (1to4) linkages | | 31 |
3088530282 | 3 classes of glycoproteins | 1)Glycoproteins
2)Proteoglycans
3)Mucins | | 32 |
3088530931 | Glycoproteins | -Mainly protein
-Part of cell membranes for cell adhesion/interaction
-Most proteins in serum are glycosylated | | 33 |
3088532764 | Proteoglycans | -Mainly Carbs
-Protein conjugated to a glycosaminoglycan
-Structural components and Lubricants | | 34 |
3088539601 | Mucins | -Mostly Carbs.
-Proteins usually bound to N-acetylgalactosamine | | 35 |
3088542822 | All N-linked glycoproteins have what? | Pentasaccharide core consisting of 3 mannoses and 2 N-Acetylglucosamines
-Additional sugars attach to this core to form variety of oligosaccharides | | 36 |
3088547764 | Erythropoietin | -Stimulates RBC count
-Glycoprotein
-Stabilized by Glycosylation
-Glycosylation is unique to the organism that produced it. | | 37 |
3088553333 | Proteoglycans | -Bound to glycosaminoglycans which determine its properties.
-Lubes and structures.
-Mediate adhesion of cells
-Bind factors that regulate cell proliferation | | 38 |
3088557063 | Glycosaminoglycans | -Repeating units of disaccharides(either glactosamine or glucosamine)
-One of the two sugars has carboylate or sulfate group
-Hyaluronate
-Chondrotien
-Chitin | | 39 |
3088560559 | Mucopolysaccharidoses | diseases from inability to degrade glycosamionglycans | | 40 |
3088583061 | Aggrecans | -shock absorber that are linked by hyaluronate(a glycosaminoglycan)
-Water absorbs into hyaluronate improving cushioning | | 41 |
3088586747 | Chitin | -Glycosaminoglycan found in exoskeleton
-second most abundant polysaccharide | | 42 |
3088588124 | Mucins | Form large polymeric structures
-Abundant in saliva
-Function as lubricants | | 43 |
3088589808 | Defining feature of mucins | Variable number of tandem repeats(VNTR)
-rich in serine and threonine residues that are O-glycosylated | | 44 |
3088592558 | O-Antigen | -Common oligosaccharide foundation for other blood antigens | | 45 |
3088593797 | A-Antigen | Addition of one N-acetyl galactosamine | | 46 |
3088596574 | B-Antigen | Addition of one galactose | | 47 |
3088596917 | Why different blood types? | Variety means protection from diseases | | 48 |
3088598501 | I-cell diseases | lysosomal storage disease
-Enzymes not tagged correctly=>end up in blood
-Have no mannose-6-phosphate on enzyme | | 49 |
3088601286 | Glycan-binding proteins | bind specific carb structure on neighboring cells
-Lectin | | 50 |
3088603118 | Lectins | -facilitate cell to cell interactions.
-Contain two or more carb-binding sites
-Link carbs via weak interactions | | 51 |
3088606148 | Selectins | -Type of lectins
-Bind to immune system cells to sites of injury in inflammatory response | | 52 |
3088613367 | | | | 53 |