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Chapter 11

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Chemistry 1210: Introduction to General Chemistry Dr. Gina M. Florio 06 Dec. 2012 Brady, Jespersen, & Hyslop Chapter 11 Properties of Gases Properties of Gases Compressible Low Density Exert Pressure (temperature dependence) Expand Mixable Some common properties of gases: While bulk properties, these intimate a molecular level foundation. Properties of Gases Recall that our understanding of kinetic energy in molecular systems relies on a molecular-level picture of gases. Kinetic Theory of Gases (CH 7) Example: Pressure Units of Pressure Standard atmosphere (atm): the pressure needed to support a column of mercury 760 mm high measures at 0 ?C The SI unit of pressure is the pascal (Pa): Pressure Measurements Open-ended Mercury Manometer:

Schizophrenia

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Schizophrenia DSM-IV Delusions Hallucinations Disorganized Speech Catatonic behavior Negative symptoms Subtypes Paranoid Delusions and hallucinations Catatonic Disorganized Disorganized speech & disorganized behavior Flat or inappropriate affect Undifferentiated Residual ? no psychotic, but negative left Syndromes Positive Delusions & Hallucinations Type I syndrome (Crow) Acute course, good prognosis, response to neuroleptics Negative Avolition, anhedonia-asociality, flat affect Type II syndrome Chronic, irreversible, poor response, intellectual impairment Disorganized Inappropriate affect, thought disorder, bizarre behavior Course Premorbid Prodrome Post episode

Psychoactive Substance Use and Disorders

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Psychoactive Substance Use Disorders Definitions DSM diagnoses Abuse: continued use despite harmful consequences Dependence: specify whether physiological dependence present Problems with younger populations Problems detecting withdrawal symptoms Frequent polydrug use Developmental status decreases impairment Stages to drug dependence Experimentation Used occasionally Routine use Change their lives to involve using & getting Addiction or dependency Powerless to resist the substance Research on Adolescents Frequency and type of use Gateway drugs abstainers Risk factors Personality traits Family relationships Friends Transition-proneness Types of substances Depressants Alcohol: patterns, risk factors Opiates Stimulants Psychedelics Etiology Biological determinants

Pervasive Developmental Disorders

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Pervasive Developmental Disorders Phenomenology & Diagnosis DSM vs. Federal guidelines Federal Guidelines Individuals with Disabilities Act ? defines autism broadly ? specify verbal and nonverbal communication and social interaction DSM-IV Autism, Asperger?s, Rett?s, Childhood Disintegrative Disorder, PDD NOS DSM-IV Criteria: Total of 6 (or more) items from 1,2, and 3 Qualitative impairment in social interaction, as manifested by at least two of following Marked impairment in multiple nonverbal behavior Failure to develop peer relationships Lack of spontaneous sharing with others Lack of social or emotional reciprocity 2) Qualitative impairment in communication ? at least 1 of: Delay in or total lack of development of spoken language

Personality Disorders

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Personality Disorders Assessment Normal vs. Abnormal personality assessment Interviews vs. questionnaires Adult vs. adolescent/children Some specific instruments designed for younger populations Stability of specific diagnoses not clear (more with younger population) Article on stability indicated that trait constellations were stable but fluctuations in meeting criteria Possible that general personality disturbance more stable Classification Problems in classifying: Reliability and validity High degree of overlap Difficulty with distinctions with normal Sexism Classification Personality traits versus disorders FFM Neuroticism, extraversion agreeableness, consientiousness, openness Longitudinal relationship betwn traits & disorders ? article

Ethical and Legal Issues

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Ethical and Legal Issues Civil (Psychiatric) Commitment Involuntary placement in a psychiatric facility (2PC) Threat to oneself or others 72 hour window until hearing or due process ? convert to voluntary commitment Different than criminal commitment (not guilty by reason of insanity) (Over)Predicting Dangerousness Best predictor of future violence is past violence! Post-hoc problem ? hindsight is 20/20 General to specific Definition of dangerousness Low base-rate Unlikely to disclose direct threats of violence Difficulty predicting behavior in community based on behavior in hospital Violence and Severe Mental Illness Increased violence in severely mentally ill BUT the increased risk of violence in schizophrenia is small

Disorders Involving Gender and Sexuality

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Disorders involving Gender and Sexuality Influence of culture How do cultural norms influence our attitudes towards sexual behaviors? Should that be reflected in the determination of mental disorders? Gender Identity Disorder Gender Identity: One?s psychological sense of being female or male Gender Identity Disorder (transsexualism): Conflict between one?s anatomic sex and one?s gender associated with serious emotional distress or impaired functioning Not caused by ?inter-sex? condition Not confused with sexual orientation Cause: Unclear? Over identification w/mom Disturbance in endocrine (hormonal) environment during gestation? Sexual Dysfunctions Persistent problems with sexual interest, arousal, or response: lifetime vs. acquired; situational vs. generalized

Chapter 10: Eating Disorders

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Eating Disorders Anorexia Nervosa Refusal to maintain minimally normal body weight Intense fear of gaining weight or becoming fat Disturbance in way in which body weight or shape is experienced, etc. Absence of at least three consecutive menstrual cycles Specify restricting type or binge/purging type Bulimia Nervosa Recurrent episodes of binge eating Recurrent inappropriate compensatory behaviors in order to prevent weight gain Binge eating & compensatory behavior occur on average 2X/week for 3 months Self-evaluation unduly influenced by weight Doesn?t occur only during anorexia Specify: Purging type or Nonpurging type Etiology Biological factors Twin studies MZ (20-50%) DZ (>10%) Family studies Hypothalmus Modulates neurotransmitters such as serotonin and norepinephrine

Chapter 7: Mood Disorders

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Mood Disorders Depressive Disorders Depressive Episodes Irritable vs. depressed mood Vegetative symptoms Endogenous symptoms Dysthymia Psychotic symptoms Double Depression Bipolar Disorders Manic episode Cyclothymia Who commits suicide? More females attempt, more males succeed. White Americans and Native Americans more likely Increased risk in elderly Etiology Psychological theories Cognitive perspective Seligman?s theory Beck?s theory Limitations ? similar, reality? Behavioral perspective Family factors Depressed parents, depressed children Stressful events (chronic, uncontrollable, beyond coping skills) Biological Factors Genetic factors MDD and dysthymia ? genetic factors account for 50%+ of variance

Chapter 5 and Chapter 6: Anxiety Disorders

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Anxiety Disorders & Responses to Stress Stress & Illness Stress and the endocrine system Stress affects the endocrine system (glands that release hormones into blood) releases ACTH, stimulates cortical steroids Chronic stress can damage bodily systems Stress and the immune system Chronic stress increases levels of interleukin-6, linked to inflammation Social support and expressing emotion through writing can help Acculturative Stress Acculturation The process of adaptation by which immigrants, native groups, and ethnic minority groups adjust to the new culture or majority culture through making behavioral and attitudinal changes Acculturative stress Pressure that results from demands placed on these groups to adjust to life in mainstream culture

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